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Depression: Psychiatry’s Discredited Theories and Drugs Versus a Sane Model and Approach

Mad in America

P sychiatry’s serotonin-imbalance theory of depression, long discarded by researchers, was finally flushed down the toilet by psychiatry and the mainstream media in 2022. And psychiatrists’ primary treatments for depression—their so-called “antidepressants”—are now circling the drain. 2) What approach to depression makes sense? Genes and depression?

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Recovery of Soul After 22 Years on Antipsychotics

Mad in America

There appears to be more dopamine uptake due to the antipsychotic-induced brain compensatory mechanism as a response to the suppressed blockade state in an effort to achieve energy equilibrium. A fter 22 years and many attempts I finally stopped taking antipsychotics.

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Day # 161: Alcohol Use Disorder (AUD)

Bullet Psych

It does this by enhancing GABA_A receptors (inhibitory neurotransmitter) and inhibiting NMDA glutamate receptors (excitatory neurotransmitter). Epidemiology & Pathogenesis 4 , 5 Genetics , environmental influences , and mental health comorbidities contribute to vulnerability. Highest rates in ages 1829.

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Do Critics of Biological Psychiatry Have an Alternative to a Life of “Whack-A-Mole”?

Mad in America

Joanna Moncrieff, Chemically Imbalanced (2025) E stablishment psychiatry has recently switched the biological cause of mental illness from a chemical imbalance to a brain circuitry defect. Challenging the biological model of depression feels like a game of whack-a-mole: as soon as you put one theory to bed, another one sprouts up.

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