Antiseizure Drug Exposure in Pregnancy Linked to Large Risk of Autism, ADHD, and Intellectual Disability
Mad in America
JUNE 3, 2024
A new systematic review finds that exposure to the antiseizure drugs valproate and topiramate during pregnancy increases the risk of autism (ASD), intellectual disability (ID), and attention deficit hyperactivity disorder (ADHD) in offspring. Valproate was associated with up to four times the risk of ASD, five times the risk of ID, and 1.5 times the risk of ADHD; topiramate was linked to a doubled risk of ASD, four times the risk of ID, and a doubled risk of ADHD.
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