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Observational Studies Confirm Trial Results That Antidepressants Double Suicides

Mad in America

One would have thought that suicide is a hard endpoint and that we can believe analyses carried out by drug regulators based on the clinical study reports the manufacturers have submitted to them, but this is not so. But as with so much else in psychiatry, this can be negotiated, obscured, and influenced by commercial conflicts of interest.

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STAR*D: The Harms of Orchestrated Psychiatric Fraud

Mad in America

We showed how STAR*D’s authors had manipulated the data to manufacture fraudulent results. Cognitive behavior therapy is described as effective, but only for mild depression—if you really need help, you are advised to choose drug treatment.