Mad in America
DECEMBER 31, 2024
Searching for the Psychiatric Yeti: Schizophrenia Is Not Genetic In January, Peter Simons wrote that the decades-long attempt to locate the gene or genes for schizophrenia has failed, according to a new article in Psychiatric Research by prominent schizophrenia researcher E. In it, he examines the concept of treatment-resistant depression.
Mad in America
DECEMBER 25, 2023
In a study of fluoxetine (Prozac) for adolescents, researchers found that the placebo effect predicted good outcomes, but the actual drug treatment did not. After accounting for “treatment guess” (those who figured out that they were receiving an intervention rather than placebo), the drug was not effective in depression treatment.
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Mad in America
DECEMBER 11, 2023
In a new article in the British Medical Journal (BMJ), 30+ prominent figures in critical psychiatry call on the UK government to acknowledge the evidence that antidepressants are no better than placebos for most patients and to increase funding of social and psychological interventions while decreasing drug prescriptions.
Mad in America
FEBRUARY 10, 2024
Editor’s Note: This article originally appeared on our affiliate site, Mad in Ireland. T he chemical imbalance theory of depression—what was once considered the gold standard reason for why people take antidepressants—was, apparently, “a figure of speech.” This is simply not the case. What are the drugs doing?
Mad in America
JANUARY 4, 2025
All of the ingredients for a blockbuster article were now clearly visible, including an acknowledgement from inside psychiatry that this story was of profound importance for all of our society. Pigott and colleagues published articles in 2015 and 2018 on the STAR*D trial, and each time Mad in America reviewed the articles.
Mad in America
APRIL 27, 2024
This was a story of a great medical advance, and the announced results from the STAR*D trial, heralded by the NIMH as the “largest and longest study ever done to evaluate depression treatment,” fit into that story of medical progress, for it told of 70% of depressed patients becoming “symptom free” after repeated treatments with antidepressants.
Mad in America
JANUARY 3, 2024
The article, written by John Miller, editor-in-chief of Psychiatric Times , prompted readers to consider the possible extraordinary harm done. Here is the cover from that issue: In his essay, Miller repeatedly stressed that ever since 2006, the STAR*D study had stood “out as a beacon guiding treatment decisions.”
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