Mad in America

MAY 2, 2024

The prevailing logic goes: if we can validate biometric tests that are clinically predictive of mental health concerns like in other medical fields, we can more precisely, effectively, and without (solely) subjective clinical observation, treat the malady. Should we give up the search for biomarkers altogether?

Trauma and the brain 111

Trauma and the brain Neurotransmitters and mental health Genetics and mental health Biopsychosocial model 111

Mad in America

FEBRUARY 24, 2024

P sychiatry’s serotonin-imbalance theory of depression, long discarded by researchers, was finally flushed down the toilet by psychiatry and the mainstream media in 2022. And psychiatrists’ primary treatments for depression—their so-called “antidepressants”—are now circling the drain. 2) What approach to depression makes sense? Genes and depression?

Poverty and mental health 145

Poverty and mental health Childhood trauma Neurotransmitters and mental health Trauma and the brain 145

Mad in America

SEPTEMBER 20, 2024

I didn’t know Wallace was a poster boy for antidepressant withdrawal because I didn’t know that antidepressant withdrawal was common, or that I would be experiencing it myself and understanding firsthand the hellish bodily and mental feelings that make one long for death, for everything to stop.

Aging and mental health 133

Aging and mental health Neurotransmitters and mental health Genetics and mental health Pharmaceuticals 133

Bullet Psych

FEBRUARY 22, 2025

It does this by enhancing GABA_A receptors (inhibitory neurotransmitter) and inhibiting NMDA glutamate receptors (excitatory neurotransmitter). Epidemiology & Pathogenesis 4 , 5 Genetics , environmental influences , and mental health comorbidities contribute to vulnerability. Highest rates in ages 1829.

Genetics and mental health 52

Genetics and mental health Neurotransmitters and mental health Trauma and the brain Aging and mental health 52