2023 Genetics and mental health Trauma and the brain 
Mad in America
MAY 2, 2024
The prevailing logic goes: if we can validate biometric tests that are clinically predictive of mental health concerns like in other medical fields, we can more precisely, effectively, and without (solely) subjective clinical observation, treat the malady. Should we give up the search for biomarkers altogether?
Mad in America
NOVEMBER 18, 2023
A fter years of work involving hundreds of people in dozens of countries, the World Health Organisation (WHO) and the United Nations Office of the High Commissioner for Human Rights (OHCHR) have released their joint production, Mental Health, Human Rights and Legislation: Guidance and Practice ( WHO/OHCHR , 2023, referred to as the Guidance.
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Mad in America
FEBRUARY 24, 2024
P sychiatry’s serotonin-imbalance theory of depression, long discarded by researchers, was finally flushed down the toilet by psychiatry and the mainstream media in 2022. And psychiatrists’ primary treatments for depression—their so-called “antidepressants”—are now circling the drain. 2) What approach to depression makes sense? Genes and depression?
Mad in America
SEPTEMBER 20, 2024
I didn’t know Wallace was a poster boy for antidepressant withdrawal because I didn’t know that antidepressant withdrawal was common, or that I would be experiencing it myself and understanding firsthand the hellish bodily and mental feelings that make one long for death, for everything to stop.
ADDitude
FEBRUARY 19, 2025
A 101 on Epigenetics Reading Genes Genes play an important role in shaping a wide range of traits and characteristics, from hair and eye color to susceptibility to mental health conditions. Yet, genetic influences are less fixed than one might think. Epigenetic alterations have been linked to numerous poor health outcomes.
Bullet Psych
FEBRUARY 22, 2025
Alcohol is reinforcing because it increases dopamine release in the brain's reward system, particularly in the mesolimbic pathway, leading to feelings of pleasure, relaxation, and euphoria. Epidemiology & Pathogenesis 4 , 5 Genetics , environmental influences , and mental health comorbidities contribute to vulnerability.
Mad in America
AUGUST 5, 2024
Editor’s Note: Mad in the UK and Mad in America are jointly publishing this four-part series on neurodiversity. The series was edited by Mad in the UK editors, and authored by John Cromby and Lucy Johnstone (with part three written by an anonymous contributor). The series is being archived here.
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