Mad in America

MAY 2, 2024

The prevailing logic goes: if we can validate biometric tests that are clinically predictive of mental health concerns like in other medical fields, we can more precisely, effectively, and without (solely) subjective clinical observation, treat the malady. Should we give up the search for biomarkers altogether?

Trauma and the brain 117

Trauma and the brain Neurotransmitters and mental health Genetics and mental health Biopsychosocial model 117

Mad in America

FEBRUARY 24, 2024

In summary, researchers have found no serotonin nor any other neurotransmitter association with depression, no neurobiological associations, and no genetic associations. The cover of the December 2023 Psychiatric Times issue announced : “STAR*D Dethroned? But What If It’s Broken?” The answer is overwhelming life pains.

Poverty and mental health 145

Poverty and mental health Childhood trauma Neurotransmitters and mental health Trauma and the brain 145

Mad in America

SEPTEMBER 20, 2024

I didn’t know Wallace was a poster boy for antidepressant withdrawal because I didn’t know that antidepressant withdrawal was common, or that I would be experiencing it myself and understanding firsthand the hellish bodily and mental feelings that make one long for death, for everything to stop. Down from 40mg.

Neurotransmitters and mental health 138

Neurotransmitters and mental health Aging and mental health Genetics and mental health Pharmaceuticals 138

Bullet Psych

FEBRUARY 22, 2025

It does this by enhancing GABA_A receptors (inhibitory neurotransmitter) and inhibiting NMDA glutamate receptors (excitatory neurotransmitter). Epidemiology & Pathogenesis 4 , 5 Genetics , environmental influences , and mental health comorbidities contribute to vulnerability. Highest rates in ages 1829.

Genetics and mental health 52

Genetics and mental health Neurotransmitters and mental health Trauma and the brain Aging and mental health 52