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It’s You, It’s Not Me: Treatment Resistant Depression and the Psychiatric Breakup

Mad in America

It showed up in the literature for the first time in 1974, when a small number of psychiatrists published some clinical observations of a “therapy resistant depression.” The therapy to which they referred was entirely pharmaceutical—it was always a failure to improve with medication. billion worldwide.

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Critical Psychiatry Textbook, Chapter 16: Is There Any Future for Psychiatry? (Part Five)

Mad in America

667 In an NIMH study of 547 patients that compared six-year outcomes for depressed people treated for the disorder and those who eschewed medical treatment, the treated patients were three times more likely than untreated ones to suffer a cessation of their principal social role and nearly seven times more likely to become incapacitated.