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Stop Using Antidepressants Except for “the Most Severe Depression,” Experts Say

Mad in America

Take, for instance, a recent meta-analysis finding that exercise is just as good as antidepressants at treating mild to moderate depression —and that adding drugs to the regimen does not improve outcomes. But they also need to stay in their place.” Is There Evidence for Antidepressant Efficacy?

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Winding Back the Clock: What If the STAR*D Investigators Had Told the Truth?

Mad in America

However, there was recognition within the NIMH that that the industry-funded trials didn’t necessarily provide evidence of the efficacy of antidepressants in real-world patients, which prompted it to launch the STAR*D study, touting it as the “largest and longest study ever done to evaluate depression treatment.”

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The New York Times Is Now Engulfed in the STAR*D Scandal

Mad in America

This was a story of a great medical advance, and the announced results from the STAR*D trial, heralded by the NIMH as the “largest and longest study ever done to evaluate depression treatment,” fit into that story of medical progress, for it told of 70% of depressed patients becoming “symptom free” after repeated treatments with antidepressants.

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Summing up the STAR*D Scandal: The Public was Betrayed, Millions were Harmed, and the Mainstream Media Failed Us All

Mad in America

American psychiatry has weathered the crisis; it will not have to confront a public stunned by news of how the oft-cited 67% cumulative remission rate, in the largest and longest study ever done to evaluate depression treatment,” was born of scientific misconduct.

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It’s You, It’s Not Me: Treatment Resistant Depression and the Psychiatric Breakup

Mad in America

The eighties and nineties were a depression-treatment renaissance. Her depression was treatment resistant but it wasn’t Justine resistant. Manufacturing Depression: The Secret History of a Modern Disorder. Is it time to abandon the concept of treatment-resistant depression? billion worldwide.

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STAR*D: The Harms of Orchestrated Psychiatric Fraud

Mad in America

They claim the study found the drugs to be effective treatments for depression, leading to remission in 67% of patients, but this is false; that finding was inflated by various types of research misconduct , even including imaginary remission rates from people who dropped out of the study.